Bowel cancer may be of the Aden carcinoma type and usually arise from the epithelium lining the inside of the large bowel which lines the large intestine. Sometimes bowel cancer is spread via the blood stream to the liver, which is the most common area of metastasis from the bowel cancer tumour. Other organs that may be affected by blood borne spread are the lungs, less often the bones, and even less often the brain.